Nasal Tumor Rounds

Key questions - please find answers from current literature for the next rounds session

Dogs

  1. What is the incidence and average age of dogs with nasal/sinus tumors?
  2. Are there any known predispositions or typical signalment of dogs who develop nasal tumors?
  3. What are the most common types of intranasal tumors? Which ones have the best long-term prognosis?
  4. What is the incidence of metastasis of nasal tumors, and the most common sites of metastasis?
  5. What are common clinical signs associated with nasal/sinus tumors, and what are potential differential diagnoses?
  6. Are there any reliable prognostic indicators for dogs with nasal tumors?
  7. What treatment options are available for dogs with nasal neoplasia? Which ones are most effective? Which ones are associated with the most complications?
  8. What is the survival time of untreated dogs with nasal carcinomas? Are there any palliative medical therapies that can improve survival time?

Cats

  1. What are the most common nasal tumors in cats?
  2. What clinical signs are seen with nasal neoplasia? Are any more apt to occur with neoplasia vs. inflammatory disease?
  3. What is the incidence and average age of cats with nasal/sinus tumors? Is there a sex predilection?
  4. What are the differential diagnosis for chronic nasal clinical signs?
  5. What are the most common tumors reported in the nasal cavity and sinuses of cats?
  6. What nasal neoplasm appears to be associated with FeLV in cats? How does its biological behavior compare with other nasal neoplasms?
  7. What treatment options are most effective for nasal LSA in cats?
  8. What treatment options have been reported for non-lymphoid feline nasal tumors?
  9. What are some prognostic factors in cats with nasal LSA?
  10. Are most cats with nasal LSA FeLV positive?
  11. What was the median survival time for cats with nasal LSA treated with megavoltage and multiagent chemotherapy?
  12. What phenotypes of nasal LSA have been reported in cats, and which one is most common?
  13. What is the treatment of choice for SCC of the nasal planum in cats? Using this treatment modality, what was the response rate? Does the diagnosis of SCC or SCC in situ affect recurrence rate, progression free survival time, or overall survival time?

General

  1. What types of diagnostic techniques are recommended for nasal disease. What is considered the gold standard for definitive diagnosis of nasal neoplasia?
  2. What are some acute phase side effects seen after RT for nasal neoplasia? Does one species (dogs vs. cats) appear to be more tolerant of RT? Are late phase RT side effects common - if so, what are they?

ARTICLES - these are in PDF format; click on each link to download the article

Please read chapter in Withrow and Vail's Veterinary Oncology text on nasal tumors

Canine and feline nasal neoplasia.pdf

Chronic nasal discharge in cats 75 cases 1993 to 2004.pdf

Evaluation of factors associated with survival in dogs with untreated nasal carcinomas 139 cases 1993 to 2003.pdf

Evaluation of strontium Sr 90 for the treatment of superficial squamous cell carcinoma of the nasal planum in cats 49 cases 1990 to 2006.pdf

Feline nasal and paranasal sinus tumours clinicopathological study, histomorphologial description and diagnostic immunohistochemistry in 123 cases.pdf

Long-term outcome of eight cats with nonlymphoproliferative nasal tumours treated by megavoltage radiotherapy.pdf

Nasal and nasopharyngeal lymphoma in cats 50 cases 1989 to 2005.pdf

Outcome of accelerated radiotherapy alone or accelerated radiotherapy followed by exenteration of the nasal cavity.pdf

Palliation of clinical signs oin 48 dogs with nasal carcinomas threated with coarse fraction radiation therapy.pdf

Photodynamic therapy for the treatment of intranasal tumors in 3 dogs and 1 cat.pdf

Response of 19 cats with nasal with nasal lymphoma to radiation therapy and chemotherapy.pdf

Retrospective study of orthovoltage radiation therapy for nasal tumors in 42 dogs.pdf

Survival in dogs with nasal adeoncarcinoma 64 cases 1981 to 1995.pdf

Treatment of 8 Dogs with Nasal Tumours with Alternating Doses of Doxorubicin and Carboplatin in Conjunction with Oral Piroxicam.pdf

Ventral Rhinotomy in the Dog and Cat.pdf

 

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